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Strengthening the competitiveness of agricultural biotechnology through practical application of gene editing technology
J Plant Biotechnol 2018;45:155-170
Published online September 30, 2018
© 2018 The Korean Society for Plant Biotechnology.

Shin-Woo Lee

Dept. of Agronomy & Medicinal Plant Resources, Gyeongnam National University of Science & Technology, JinJu, Korea
Correspondence to: e-mail:
Received July 3, 2018; Revised September 4, 2018; Accepted September 12, 2018.
cc This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
In this paper, mechanisms of gene editing technologies including ZFN, TALENS and CRISPR were briefly discussed with mutual advantages and disadvantages. Classification criteria of gene edited, site-directed mutagenesis (SDN) crops for regulatory purpose were also discussed. The number of studies using CRISPR technology was high and studies conducted on Arabidopsis thaliana and rice were highest, followed by tobacco, tomato, wheat, and corn. It has been applied to a variety of plants such as other grain crops, flower crops, vegetable crops, and fruit trees. The number of studies focused on practical application or commercialization in the future were also increasing yearly, and the scope of studies also expanded to include research on metabolic engineering for mass production of useful proteins or substances, development of disease resistant crops against viruses, bacteria, and fungi, abiotic environmental stressresistant crops, and increased yields. In addition to this, it was revealed that application range is becoming more diversified, including the development of parthenocarpic tomatoes, hybrid rice lines using male sterility and increased shattering resistance Brassica napus. It was also revealed that the number of CRISPR gene edited crops permitted by the USDA(APHIS) increases yearly, to be released in the international seed market soon.
Keywords : Gene Editing, SDN, Publications, Practical Application, Agricultural Biotechnology

September 2018, 45 (3)
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