Review

J Plant Biotechnol 2014; 41(4): 169-179

Published online December 31, 2014

© The Korean Society of Plant Biotechnology

Metabolic engineering for biofortification of lipophilic antioxidants in plants

Eun-Ha Kim, Kyeong-Ryeol Lee, Jong-Bum Kim, Kyung Hee Roh, Han Chul Kang, Hyun Uk Kim

Correspondence to :

E.-H. Kim?K.-R. Lee ?J.-B. Kim?K. H. Roh ? H. C. Kang ? H. U. Kim

Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration, Jeonju 560-500, Republic of Korea
e-mail: hukim64@korea.kr

Received: 8 October 2014; Revised: 25 October 2014; Accepted: 27 October 2014

Abstract

Metabolic engineering for biofortification of lipophilic antioxidantaIntracellular antioxidants include low molecular weight scavengers of oxidizing species, and enzymes which degrade superoxide and hydroperoxides. Such antioxidants systems prevent oxidative damage to cellular component by scavenging free radicals and activated oxygen species. Hydrophobic scavengers are found in cell membrane where they interrupt chain reactions of lipid peroxidation. The three major lipophilic antioxidant classes for human health are carotenoids, vitamin E and coenzyme Q10. The biofortification of staple crops with these lipid soluble antioxidants is an attractive strategy to increase the nutritional quality of human food. Here, we have summarized the biosynthetic pathways of three lipid soluble antioxidants in plants and current status of genetic engineered plants for elevated levels of each lipophilic antioxidant.s in plants

Article

Review

J Plant Biotechnol 2014; 41(4): 169-179

Published online December 31, 2014

Copyright © The Korean Society of Plant Biotechnology.

Metabolic engineering for biofortification of lipophilic antioxidants in plants

Eun-Ha Kim, Kyeong-Ryeol Lee, Jong-Bum Kim, Kyung Hee Roh, Han Chul Kang, Hyun Uk Kim

Correspondence to:

E.-H. Kim?K.-R. Lee ?J.-B. Kim?K. H. Roh ? H. C. Kang ? H. U. Kim

Department of Agricultural Biotechnology, National Academy of Agricultural Science, Rural Development Administration, Jeonju 560-500, Republic of Korea
e-mail: hukim64@korea.kr

Received: 8 October 2014; Revised: 25 October 2014; Accepted: 27 October 2014

Abstract

Metabolic engineering for biofortification of lipophilic antioxidantaIntracellular antioxidants include low molecular weight scavengers of oxidizing species, and enzymes which degrade superoxide and hydroperoxides. Such antioxidants systems prevent oxidative damage to cellular component by scavenging free radicals and activated oxygen species. Hydrophobic scavengers are found in cell membrane where they interrupt chain reactions of lipid peroxidation. The three major lipophilic antioxidant classes for human health are carotenoids, vitamin E and coenzyme Q10. The biofortification of staple crops with these lipid soluble antioxidants is an attractive strategy to increase the nutritional quality of human food. Here, we have summarized the biosynthetic pathways of three lipid soluble antioxidants in plants and current status of genetic engineered plants for elevated levels of each lipophilic antioxidant.s in plants

JPB
Vol 51. 2024

Stats or Metrics

Share this article on

  • line

Journal of

Plant Biotechnology

pISSN 1229-2818
eISSN 2384-1397
qr-code Download